A-Spine Holding Group Corp. (ASH) and its subsidiaries, invest in, develop, manufacture, market and distribute orthopedic products worldwide. ASH has more than 20 years of experience in the spinal market and consists of three wholly owned subsidiaries: A-Spine Asia Co., Ltd., A-Spine USA, Inc., and A-Spine Research Inc. located in Taiwan, the United States and Japan respectively.

The predecessor to ASH, A-Spine Inc. (ASI), was formed in Japan in May of 2001. CMT's rich intellectual property portfolio (with over 120 patents), global sales network and innovative research & development with Ammtec, one of the largest distributor networks in Japan, combined to form a new leader in the orthopedic market. In June 2001, venture capital from President Life Science Cayman Co. (PLS) and JAFCO Co. Ltd. of Japan brought together two additional companies with strength and insight. PLS, part of the Uni-President Group, one of Asia-Pacificlargest conglomerates, well-known in Greater China for its investment diversifications and active role in the biotech field, and JAFCO, one of Japan  largest venture capitalists, a company known for its visionary and profitable investments in developing fields, all came together with a capital investment of 4,500,000 US Dollars realizing the orthopedic market  great potential.

Concurrently, due to considerations of a rapid expanding global market and the need for a sales force more attuned to local market trends, A-Spine Asia and A-Spine USA was established in Taiwan and the US giving ASH a presence in the world's  largest orthopedic market.

A-Spine Holding Group Corp. was established in the British Virgin Islands, March 2002, replacing ASI due in part to the financial benefits associated with establishing business there. ASH thus became the new parent company of A-Spine Asia, A-Spine USA, and the later formed A-Spine Research Inc. (ASR). ASR was established in Japan in June 2002 placing it in a favorable position in the world  second largest market, allowing it to focus on the rapid projected growth there.